January 22, 2021

USH2A is a Meissner’s corpuscle protein necessary for normal vibration sensing in mice and humans

Nature Neuroscience, Published online: 07 December 2020; doi:10.1038/s41593-020-00751-y

Schwaller et al. show that the USH2A protein, present in Meissner’s corpuscles, is necessary in humans and mice to perceive tiny vibrations. USH2A may facilitate force transfer to mechanoreceptors as the fingertip probes rough surfaces.

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