November 24, 2020

Tipping the Scales: Peptide-Dependent Dysregulation of Neural Circuit Dynamics in Alzheimer’s Disease

Evidence indicates synergistic and antagonistic effects of Alzheimer disease (AD)-related peptides on neuronal circuit excitability. Here, Harris et al. discuss the mechanistic underpinnings and present a circuit-based framework of AD progression with novel prospects for diagnosis and therapy.


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