January 20, 2021

Spinal astrocytes in superficial laminae gate brainstem descending control of mechanosensory hypersensitivity

Nature Neuroscience, Published online: 05 October 2020; doi:10.1038/s41593-020-00713-4

Kohro et al. identify a population of astrocytes located in the superficial dorsal horn of adult spinal cord (genetically defined by Hes5) that acts as a gate for locus coeruleus descending noradrenergic control of mechanosensory hypersensitivity.

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