October 21, 2020

Single Cell Technologies Define New Therapeutic Avenues for Huntington’s Disease

Using two independent single-cell transcriptomics technologies, Lee et al. have cataloged transcriptional changes in the subset of striatal neurons hit hardest in Huntington’s disease. One downregulated pathway, oxidative phosphorylation, may also explain their observed release of mitochondrial-encoded RNAs.

 Neuron

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