November 28, 2020

Regulation of autism-relevant behaviors by cerebellar–prefrontal cortical circuits

Nature Neuroscience, Published online: 13 July 2020; doi:10.1038/s41593-020-0665-z

Kelly et al. describe two cerebellum–thalamus–mPFC pathways in mice that regulate social and repetitive behavior. PC activation in Rcrus1 and posterior vermis improved social and reduced repetitive behaviors, respectively, in PC-Tsc1 mutant mice.

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