May 18, 2021

Asthma and allergies more common in teens who stay up late

Teenagers who prefer to stay up late and wake later in the morning are more likely to suffer with asthma and allergies compared to those who sleep and wake earlier, …

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Marijuana use while pregnant boosts risk of children’s sleep problems

As many as 7% of moms-to-be use marijuana while pregnant, and that number is rising fast as more use it to quell morning sickness. But new research suggests such use …

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Infant sleep problems can signal mental disorders in adolescents

Specific sleep problems among babies and very young children can be linked to mental disorders in adolescents, a new study has found.  Sleep Disorders News — ScienceDaily  Read More

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Circadian photoperiod alters TREK-1 channel function and expression in dorsal raphe serotonergic neurons

Seasonal daylength has been linked to the development and prevalence of mood disorders, however, the neural mechanisms underlying this relationship remain unknown. Previous work in our laboratory has shown that …

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Caudal-rostral progression of alpha motoneurone degeneration in the SOD1G93A mouse model of amyotrophic lateral sclerosis

Mice with transgenic expression of human SOD1G93A are a widely used model of ALS, with a caudal-rostral progression of motor impairment. Previous studies have quantified the progression of motoneurone (MN) …

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Mesoscopic cortical network reorganization during recovery of partial optic nerve injury in GCaMP6s mice

As the residual vision following a traumatic optic nerve injury can spontaneously recover over time, we explored the plasticity of cortical networks during the early post-optic nerve crush (ONC) phase. …

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The language of mental images: Characterizing hippocampal contributions to imageable word use during event construction

Accumulating evidence suggests that the hippocampus plays a critical role in the creative and flexible use of language. For example, amnesic patients with hippocampal damage produce less coherent and cohesive …

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Altered Affective Behaviors in Casein Kinase 1 Epsilon Mutant Mice

Affective behaviors and mental health are profoundly affected by disturbances in circadian rhythms. Casein kinase 1 epsilon (Csnk1e) is an essential component of the core circadian clock. Mice with tau …

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Obesity impairs cognitive function via metabolic syndrome and cerebrovascular disease: an SEM analysis in 15,000 adults from the UK Biobank.

Chronic obesity is associated with several complications, including cognitive impairment and dementia. However, we have piecemeal knowledge of the mechanisms linking obesity to central nervous system damage. Adiposity leads to …

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Quantitative trait locus mapping identifies Col4a6 as a novel regulator of striatal dopamine level and axonal branching in mice.

The features of dopaminergic neurons (DAns) of nigrostriatal circuitry are orchestrated by a multitude of yet unknown factors, many of them genetic. Genetic variation between individuals at baseline can lead …

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