November 27, 2020

Memory trace interference impairs recall in a mouse model of Alzheimer’s disease

Nature Neuroscience, Published online: 08 June 2020; doi:10.1038/s41593-020-0652-4

Mice with AD-like pathology and memory impairments surprisingly have memory engrams in their hippocampus. However, interference with novelty-like cells prevents proper recall, erroneously letting mice perceive a previously learned context as novel.

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