April 15, 2021

Machine learning reveals bilateral distribution of somatic L1 insertions in human neurons and glia

Nature Neuroscience, Published online: 11 January 2021; doi:10.1038/s41593-020-00767-4

Zhu et al. discover that in human brain there is widespread anatomic distribution of low-frequency somatic, mosaic L1 insertions, using deep whole-genome sequencing of neuronal and glial fractions and machine-learning analysis.

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