Nature Neuroscience, Published online: 22 February 2021; doi:10.1038/s41593-021-00802-y
Gordon et al. use genome-wide unbiased approaches to show that human cerebral cortical organoids, when cultured for many months, start to resemble stages of postnatal brain development, with a timeline that parallels in vivo development.
Long-term maturation of human cortical organoids matches key early postnatal transitions
