November 23, 2020

High-fat food biases hypothalamic and mesolimbic expression of consummatory drives

Nature Neuroscience, Published online: 03 August 2020; doi:10.1038/s41593-020-0684-9

Mazzone and Liang-Guallpa et al. demonstrate that consuming high-fat foods rapidly and durably tunes parallel brain circuits to drive intake of a high-fat diet while devaluing a nutritionally balanced, standard diet even under states of intense hunger.

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