April 14, 2021

CNS fibroblasts form a fibrotic scar in response to immune cell infiltration

Nature Neuroscience, Published online: 01 February 2021; doi:10.1038/s41593-020-00770-9

Dorrier et al. identified fibrotic scarring in a mouse model of multiple sclerosis that arises from the proliferation of fibroblasts in the meninges and surrounding blood vessels, and determine that reducing scarring decreases motor symptom severity.

 
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