April 20, 2021

Closing the gate to distractors during decision-making

Nature Neuroscience, Published online: 19 April 2021; doi:10.1038/s41593-021-00833-5 The act of remembering information or planning actions in short term memory can often be robust to distracting or conflicting information. Finkelstein …

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From base pair to brain

Nature Neuroscience, Published online: 19 April 2021; doi:10.1038/s41593-021-00852-2 In new research, Smith et al. identify thousands of novel genetic associations with human brain structure and function, including those on the …

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An expanded set of genome-wide association studies of brain imaging phenotypes in UK Biobank

Nature Neuroscience, Published online: 19 April 2021; doi:10.1038/s41593-021-00826-4 The Elliott and Smith teams used imaging and genetics data from 40,000 volunteers in the UK Biobank healthcare study, discovering new genetic …

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Attractor dynamics gate cortical information flow during decision-making

Nature Neuroscience, Published online: 19 April 2021; doi:10.1038/s41593-021-00840-6 The flow of information in the brain is regulated over space and time. The authors show that mice can adaptively filter stimuli …

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Multimodal neural recordings with Neuro-FITM uncover diverse patterns of cortical–hippocampal interactions

Nature Neuroscience, Published online: 19 April 2021; doi:10.1038/s41593-021-00841-5 Liu et al. present a flexible, insertable and transparent microelectrode (FITM) array termed Neuro-FITM. Multimodal recordings with Neuro-FITM reveal diverse and selective …

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Remapping and realignment in the human hippocampal formation predict context-dependent spatial behavior

Nature Neuroscience, Published online: 15 April 2021; doi:10.1038/s41593-021-00835-3 Julian and Doeller show that trial-by-trial modulation of map-like representations in the human hippocampal–entorhinal system predicts contextual memory retrieval during virtual reality …

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Rescue of maternal immune activation-induced behavioral abnormalities in adult mouse offspring by pathogen-activated maternal Treg cells

Nature Neuroscience, Published online: 15 April 2021; doi:10.1038/s41593-021-00837-1 Xu et al. developed and characterized a new animal model of maternal immune activation based on a parasite mimetic. They show that …

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Brain proteome-wide association study implicates novel proteins in depression pathogenesis

Nature Neuroscience, Published online: 12 April 2021; doi:10.1038/s41593-021-00832-6 Wingo et al. integrate depression GWAS results with human brain proteomes to perform proteome-wide association studies followed by Mendelian randomization. They identify …

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Flexible modulation of sequence generation in the entorhinal–hippocampal system

Nature Neuroscience, Published online: 12 April 2021; doi:10.1038/s41593-021-00831-7 McNamee et al. develop a theory of entorhinal–hippocampal processing. Distributed entorhinal input drives hippocampal activity between distinct statistical and dynamical regimes of …

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Author Correction: Long-term behavioral and cell-type-specific molecular effects of early life stress are mediated by H3K79me2 dynamics in medium spiny neurons

Nature Neuroscience, Published online: 08 April 2021; doi:10.1038/s41593-021-00848-y Author Correction: Long-term behavioral and cell-type-specific molecular effects of early life stress are mediated by H3K79me2 dynamics in medium spiny neurons   …

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