April 14, 2021

Brain microvasculature has a common topology with local differences in geometry that match metabolic load

Ji et al. constructed the whole mouse brain microvascular connectome. Their analysis reveals a common network topology that leads to shared robustness against vessel rarefaction and stalled RBCs, while a heterogeneous network geometry matches the rate of regional resting metabolism to maintain a common maximum oxygen tension throughout the brain.

 Neuron

 Read More

Leave a Reply

%d bloggers like this: