January 19, 2021

Acute targeting of pre-amyloid seeds in transgenic mice reduces Alzheimer-like pathology later in life

Nature Neuroscience, Published online: 16 November 2020; doi:10.1038/s41593-020-00737-w

Uhlmann et al. show that the preclinical phase of Alzheimer’s disease may in fact be a relatively late manifestation of a much earlier pathogenic and targetable process of seed formation and propagation.

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