October 29, 2020

A prefrontal–paraventricular thalamus circuit requires juvenile social experience to regulate adult sociability in mice

Nature Neuroscience, Published online: 31 August 2020; doi:10.1038/s41593-020-0695-6

Yamamuro et al. show that juvenile social isolation disrupts prefrontal neurons projecting to the paraventricular thalamus and associated prefrontal somatostatin interneurons, and thereby impairs sociability in adulthood.

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