October 20, 2020

A glycolytic shift in Schwann cells supports injured axons

Nature Neuroscience, Published online: 17 August 2020; doi:10.1038/s41593-020-0689-4

Babetto et al. demonstrate an axonal injury-induced glycolytic surge in Schwann cells that supplies perturbed axons with glycolytic energy substrates. Disruption of this metabolic coupling of axons and glial cells promotes axonal degeneration.

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