February 25, 2021

Mental individuation of imagined finger movements can be achieved using TMS-based neurofeedback

Neurofeedback (NF) in combination with motor imagery (MI) can be used for training individuals to volitionally modulate sensorimotor activity without producing overt movements. However, until now, NF methods were of …

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New experiences enhance learning by resetting key brain circuit

A study of spatial learning in mice shows that exposure to new experiences dampens established representations in the brain’s hippocampus and prefrontal cortex, allowing the mice to learn new navigation …

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Neural correlates of subsequent memory-related gaze reinstatement

Mounting evidence linking gaze reinstatement- the recapitulation of encoding-related gaze patterns during retrieval- to behavioral measures of memory suggests that eye movements play an important role in mnemonic processing. Yet, …

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Glia-neuron signaling mediated by two different BMP ligands impacts synaptic growth

The nervous system is a complex network of cells whose interactions provide circuitry necessary for an organism to perceive and move through its environment. Revealing the molecular basis of how …

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Distrust Before First Sight: Knowledge- and Appearance-Based Effects of Trustworthiness on the Visual Consciousness of Faces

Not all visual stimuli processed by the brain reach the level of conscious perception. Previous research has shown that the emotional value of a stimulus is one of the factors …

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Previous estradiol treatment during midlife maintains transcriptional regulation of memory-related proteins by ERα in the hippocampus in a rat model of menopause

Previous midlife estradiol treatment, like continuous treatment, improves memory and results in lasting increases in hippocampal levels of estrogen receptor (ER) and ER-dependent transcription in ovariectomized rodents. We hypothesized that …

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Altered environmental perception by parental stress and depression vulnerability: impact on mothers and offspring

Depressive mothers often find the mother-child interaction to be challenging. Parental stress may further impair mother-child attachment, which may increase the risk of negative developmental consequences. We used rats with …

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Deep Brain Stimulation for Parkinson’s Disease Induces Spontaneous Cortical Hypersynchrony In Extended Motor and Cognitive Networks

The mechanism of action of deep brain stimulation (DBS) for Parkinson’s disease remains unclear. Studies have shown that DBS decreases pathological beta hypersynchrony between the basal ganglia and motor cortex. …

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Astrocyte nanoscale morphology controls Ca2+ signals at tripartite synapses

Ca2+ signals in astrocytes can trigger the modulation of neuronal activity. Recent developments in Ca2+ imaging and super-resolution microscopy have allowed to characterize the complex morphology of astrocyte branchlets that …

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Widespread ripples synchronize human cortical activity

Hippocampal ripples index the reconstruction of spatiotemporal neuronal firing patterns essential for the consolidation of memories in cortex during sleep. Here, using human intracranial recordings, we show that ripples are …

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